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Which Vaccines Should I Check Before Pregnancy?

Some infections can be more serious during pregnancy or affect a developing baby. Checking your vaccination history before conception gives you time to receive vaccines that may be recommended before rather than during pregnancy.

7 min readBy Jeni Team9/2/2026

Educational only — not medical advice. If you have urgent symptoms, seek medical care.

When preparing for pregnancy, you may think about:

  • folic acid

  • healthy food

  • your fertile window

  • medicines

But there is another important question:

“Are my vaccinations up to date?”

Some infections can cause more serious illness during pregnancy.

Others can affect the developing baby.

Checking before pregnancy gives you time to address gaps safely.

Quick Answer

Before trying to conceive, review your vaccination history with a healthcare professional.

Vaccines that may be particularly relevant include protection against infections such as:

  • rubella

  • hepatitis B

  • influenza

  • tetanus, diphtheria and pertussis according to national recommendations

  • COVID-19 where recommended

  • other infections based on your age, health, occupation, travel and vaccination history

Not everyone needs every vaccine.

The right vaccines depend on your individual history and Ghana's current immunization recommendations.

Why Check Before Pregnancy?

There are two main reasons.

First:

some infections are particularly dangerous during pregnancy.

Second:

some vaccines are preferably given before pregnancy rather than during it.

If you wait until the pregnancy test is positive, some options may need to be postponed.

Are Vaccines Safe When Planning Pregnancy?

Many vaccines can be safely given around the time you are planning pregnancy.

But vaccines are not all the same.

A useful distinction is between:

live vaccines

and:

non-live vaccines.

This matters because certain live vaccines are generally avoided during pregnancy.

What Is a Live Vaccine?

A live attenuated vaccine contains a weakened form of the organism that causes the infection.

It is weakened enough to stimulate immunity without causing the usual disease in healthy people.

Because of theoretical concerns about fetal infection, certain live vaccines are generally not recommended during pregnancy.

That is why checking your vaccination status before conception is useful.

Rubella: One of the Most Important Pre-Pregnancy Checks

Rubella—sometimes called German measles—can be mild in adults.

But infection during pregnancy, particularly early pregnancy, can have serious consequences for the developing baby.

It can cause congenital rubella syndrome.

This may affect:

  • hearing

  • vision

  • heart development

  • other organs

Preventing rubella before pregnancy is therefore important.

How Do I Know If I Am Protected Against Rubella?

Your healthcare professional may review:

  • vaccination records

  • previous documented immunity

  • testing where appropriate

Do not assume you are unprotected simply because you cannot remember receiving the vaccine.

But if your vaccination status is uncertain, ask.

Can I Receive a Rubella-Containing Vaccine During Pregnancy?

Rubella-containing vaccines such as MMR are live vaccines and are generally not given during pregnancy.

If vaccination is needed, it is usually given before conception or after pregnancy.

How Long Should I Wait After a Rubella-Containing Vaccine?

Guidance commonly recommends avoiding pregnancy for about one month after MMR vaccination.

Your healthcare professional should give you the specific recommendation that applies to the vaccine you receive.

What If I Accidentally Become Pregnant After MMR?

Do not panic.

Accidental vaccination around conception is not usually considered a reason by itself to end a pregnancy.

Contact your healthcare professional so the situation can be reviewed appropriately.

What About Hepatitis B?

Hepatitis B can cause chronic liver disease and can be transmitted from mother to baby.

If you are at risk and have not been vaccinated, hepatitis B vaccination may be recommended.

Risk factors may include:

  • occupational exposure to blood

  • living with someone with hepatitis B

  • sexual exposure

  • certain medical procedures or conditions

Your healthcare professional can determine whether vaccination or testing is appropriate.

Can Hepatitis B Vaccine Be Given During Pregnancy?

Hepatitis B vaccines are non-live vaccines and may be used during pregnancy when indicated.

However, if you are planning pregnancy now, reviewing your status beforehand gives you an opportunity to begin or complete vaccination when appropriate.

What About Tetanus?

Protection against tetanus is important for maternal and newborn health.

Recommendations vary according to:

  • previous vaccination

  • national immunization schedules

  • pregnancy history

In Ghana, maternal immunization services include tetanus-containing vaccination according to national guidance.

Your antenatal team will review this during pregnancy.

What About Whooping Cough?

Whooping cough—pertussis—can be particularly dangerous for newborn babies.

In countries where maternal pertussis vaccination is recommended, it is usually given during a specific period of each pregnancy so maternal antibodies can pass to the baby.

This is different from vaccines that are mainly checked before conception.

Follow current Ghanaian guidance regarding availability and recommendations.

What About Influenza?

Pregnancy increases the risk of severe illness from influenza.

Inactivated influenza vaccines can be given during pregnancy and are recommended for pregnant people in many settings where available.

If you are planning pregnancy, ask about local recommendations and availability.

What About COVID-19 Vaccination?

COVID-19 vaccination recommendations may change as evidence, circulating variants and national programmes evolve.

Pregnancy itself can increase the risk of severe COVID-19.

If you are planning pregnancy, ask your healthcare professional about the current Ghana Health Service recommendations for COVID-19 vaccination.

What About Chickenpox?

Varicella—or chickenpox—can cause serious illness during pregnancy and, in certain circumstances, affect the baby.

If you have never had chickenpox and have not been vaccinated, discuss this with a healthcare professional.

The varicella vaccine is a live vaccine and is generally given before, not during, pregnancy where it is indicated and available.

Do I Need Every Childhood Vaccine Again?

No.

The goal is not to restart your entire childhood vaccination schedule.

Your healthcare professional should determine:

  • what you have already received

  • whether you completed the recommended doses

  • whether boosters are required

  • whether particular risks apply to you

What If I Lost My Vaccination Card?

This happens frequently.

Tell the healthcare professional what you know.

Depending on the vaccine and your circumstances, they may use:

  • available medical records

  • your vaccination history

  • testing for immunity in selected situations

  • revaccination when appropriate

Do not let a missing card prevent you from asking.

Do I Need Blood Tests for Every Vaccine?

No.

Routine blood testing for immunity to every vaccine-preventable infection is not necessary.

Testing is useful only in specific circumstances.

Your clinician can decide what is appropriate.

What If I Am Travelling Before Pregnancy?

Travel can change your vaccination needs.

Some destinations may have risks such as:

  • yellow fever

  • hepatitis A

  • meningococcal disease

  • other infections

Some travel vaccines have special considerations around pregnancy.

If you are planning international travel and pregnancy at the same time, seek travel-health advice early.

What About Yellow Fever?

Yellow fever vaccination is a live vaccine.

The decision around vaccination in someone who is pregnant or planning pregnancy depends on the actual risk of yellow fever exposure and travel requirements.

This can be particularly relevant for travellers from or within parts of Africa.

Do not make the decision based only on internet advice.

Discuss your destination and timing with a qualified healthcare professional or travel clinic.

Can Vaccines Cause Infertility?

Routine recommended vaccines have not been shown to cause infertility.

Claims that vaccination permanently damages fertility should be evaluated against reliable medical evidence.

If you have concerns about a specific vaccine, discuss the actual evidence with a healthcare professional.

Do Vaccines “Overload” My Body Before Pregnancy?

No.

Your immune system encounters many substances every day.

Vaccination trains the immune system to recognize specific infections.

Receiving recommended vaccines does not use up your immune system or make it unable to support pregnancy.

What About My Partner?

Your partner should also be appropriately vaccinated.

This protects his health and can reduce the chance of bringing certain infections into the household.

This becomes particularly important once there is a newborn who may be too young to have completed their own vaccinations.

Should I Delay Pregnancy to Complete Vaccination?

It depends on the vaccine.

For some vaccines, there is no need to delay conception.

For certain live vaccines, you may be advised to wait for a specified period after vaccination.

Ask:

“Do I need to wait before trying to conceive after this vaccine?”

Do not assume.

What If I Become Pregnant Before Completing a Vaccine Series?

Tell your healthcare professional.

Whether remaining doses can be given during pregnancy depends on the specific vaccine.

Some can continue.

Others may be postponed.

Do not restart an entire series unless specifically advised.

What Should I Bring to My Pre-Pregnancy Appointment?

If available, bring:

  • childhood vaccination records

  • previous antenatal records

  • vaccination cards

  • occupational vaccination records

  • travel vaccination certificates

Even incomplete records can help.

A Simple Vaccine Checklist

Before trying for pregnancy, ask:

Am I protected against rubella?

Do I need hepatitis B vaccination or testing?

Are my routine vaccines up to date?

Are there vaccines recommended because of my medical condition or job?

Am I travelling somewhere that changes my vaccination needs?

Is there any vaccine I need to receive before pregnancy rather than during it?

Do I need to wait before trying after any vaccine I receive?

Remember This

Vaccination is part of preparing for pregnancy because some infections are easier to prevent before they threaten you or your baby.

The key is not to collect as many vaccines as possible.

It is to know:

what you have already received

what protection you need

which vaccines are best given before pregnancy

which are recommended during pregnancy.

Pay particular attention to rubella immunity, because rubella infection during early pregnancy can seriously affect fetal development and rubella-containing vaccines are generally not given once you are pregnant.

Review your vaccination history before you start trying, and follow current national guidance for the vaccines that apply to you.

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  • PREP-007: Why Should I Have a Pre-Pregnancy Health Check?

  • PREP-008: Which Health Conditions Should Be Controlled Before Pregnancy?

  • PREP-009: Are My Medicines Safe If I Am Trying to Get Pregnant?

  • PREP-011: How Do Smoking, Alcohol and Drugs Affect My Chances of Pregnancy?